Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
692decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Bitterbloom Bearer
3.3%inclusion3 decks91 decks
1%synergy
Bender's Waterskin
2.6%inclusion3 decks114 decks
2%synergy
Swampsnare Trap
1.6%inclusion1 decks64 decks
1%synergy
Koh, the Face Stealer
1.6%inclusion1 decks64 decks
0%synergy
Realm of Koh
1.6%inclusion1 decks64 decks
-2%synergy
High Synergy Cards
Plague Stinger
81%inclusion561 decks692 decks
80%synergy
Plague Myr
79%inclusion544 decks692 decks
77%synergy
Ichor Rats
79%inclusion544 decks692 decks
75%synergy
Hand of the Praetors
76%inclusion527 decks692 decks
75%synergy
Infectious Inquiry
76%inclusion527 decks692 decks
73%synergy
Vraska's Fall
71%inclusion490 decks692 decks
67%synergy
Whispering Specter
67%inclusion467 decks692 decks
67%synergy
Karn's Bastion
69%inclusion476 decks692 decks
65%synergy
Phyrexian Crusader
65%inclusion451 decks692 decks
64%synergy
Drown in Ichor
66%inclusion455 decks692 decks
61%synergy
Top Cards
Dark Ritual
79%inclusion547 decks692 decks
13%synergy
Lashwrithe
64%inclusion444 decks692 decks
60%synergy
Swiftfoot Boots
63%inclusion438 decks692 decks
32%synergy
Jet Medallion
63%inclusion434 decks692 decks
2%synergy
Blightbelly Rat
61%inclusion425 decks692 decks
58%synergy
Phyrexian Arena
61%inclusion423 decks692 decks
21%synergy
Crypt Ghast
61%inclusion422 decks692 decks
13%synergy
Phyresis Outbreak
60%inclusion418 decks692 decks
59%synergy
Sign in Blood
58%inclusion401 decks692 decks
22%synergy
Nightmare Lash
57%inclusion397 decks692 decks
55%synergy
Game Changers
Demonic Tutor
42%inclusion292 decks692 decks
15%synergy
Vampiric Tutor
31%inclusion215 decks692 decks
10%synergy
Necropotence
22%inclusion153 decks692 decks
7%synergy
Ancient Tomb
21%inclusion147 decks692 decks
9%synergy
Bolas's Citadel
16%inclusion113 decks692 decks
-13%synergy
Mana Vault
15%inclusion105 decks692 decks
8%synergy
Opposition Agent
13%inclusion90 decks692 decks
3%synergy
The One Ring
12%inclusion80 decks692 decks
2%synergy
Chrome Mox
11%inclusion73 decks692 decks
4%synergy
Imperial Seal
9.2%inclusion64 decks692 decks
2%synergy
Creatures
Reaper of Sheoldred
54%inclusion372 decks692 decks
53%synergy
Ichorclaw Myr
47%inclusion325 decks692 decks
46%synergy
Flensermite
45%inclusion313 decks692 decks
45%synergy
Core Prowler
44%inclusion306 decks692 decks
44%synergy
Bilious Skulldweller
44%inclusion302 decks692 decks
43%synergy
Corpse Cur
43%inclusion299 decks692 decks
43%synergy
Flesh-Eater Imp
39%inclusion269 decks692 decks
38%synergy
Pestilent Syphoner
38%inclusion263 decks692 decks
37%synergy
Septic Rats
36%inclusion251 decks692 decks
34%synergy
Phyrexian Obliterator
35%inclusion241 decks692 decks
24%synergy
K'rrik, Son of Yawgmoth
31%inclusion213 decks692 decks
12%synergy
Necropede
29%inclusion198 decks692 decks
28%synergy
Myr Convert
27%inclusion187 decks692 decks
26%synergy
Yawgmoth, Thran Physician
24%inclusion168 decks692 decks
14%synergy
Blightsteel Colossus
22%inclusion154 decks692 decks
22%synergy
Solemn Simulacrum
22%inclusion152 decks692 decks
-1%synergy
Gray Merchant of Asphodel
22%inclusion151 decks692 decks
-30%synergy
Contagious Nim
21%inclusion146 decks692 decks
21%synergy
Leaden Myr
20%inclusion136 decks692 decks
13%synergy
Gulping Scraptrap
18%inclusion127 decks692 decks
18%synergy
Blackcleave Goblin
18%inclusion122 decks692 decks
17%synergy
Phyrexian Juggernaut
16%inclusion109 decks692 decks
16%synergy
Magus of the Coffers
15%inclusion103 decks692 decks
8%synergy
Massacre Girl, Known Killer
15%inclusion101 decks692 decks
11%synergy
Defiler of Flesh
14%inclusion98 decks692 decks
10%synergy
Necroskitter
14%inclusion96 decks692 decks
10%synergy
Dauthi Voidwalker
14%inclusion96 decks692 decks
-2%synergy
Sheoldred, Whispering One
13%inclusion91 decks692 decks
1%synergy
Phyrexian Vatmother
13%inclusion90 decks692 decks
13%synergy
Dread Presence
13%inclusion88 decks692 decks
-2%synergy
Toxic Nim
12%inclusion86 decks692 decks
12%synergy
Grafted Butcher
12%inclusion84 decks692 decks
12%synergy
Filth
11%inclusion79 decks692 decks
9%synergy
Sheoldred's Headcleaver
11%inclusion79 decks692 decks
11%synergy
Dark Confidant
11%inclusion77 decks692 decks
4%synergy
Silent Arbiter
10%inclusion68 decks692 decks
8%synergy
Nirkana Revenant
9.4%inclusion65 decks692 decks
-2%synergy
Phyrexian Digester
9.4%inclusion65 decks692 decks
9%synergy
Sheoldred, the Apocalypse
9.1%inclusion63 decks692 decks
-6%synergy
Burnished Hart
8.7%inclusion60 decks692 decks
1%synergy
Maha, Its Feathers Night
8.1%inclusion39 decks480 decks
3%synergy
Nimraiser Paladin
8.1%inclusion56 decks692 decks
8%synergy
Orcish Bowmasters
8.1%inclusion56 decks692 decks
-6%synergy
Vector Asp
7.8%inclusion54 decks692 decks
8%synergy
Massacre Wurm
6.9%inclusion48 decks692 decks
-11%synergy
Gwenom, Remorseless
6.9%inclusion8 decks116 decks
4%synergy
Swamp Mosquito
6.8%inclusion47 decks692 decks
7%synergy
Brass Squire
6.8%inclusion47 decks692 decks
6%synergy
Scourge Servant
6.6%inclusion46 decks692 decks
7%synergy
Surge Conductor
6.4%inclusion8 decks125 decks
6%synergy
Instants
Howl from Beyond
52%inclusion357 decks692 decks
51%synergy
Whisper of the Dross
47%inclusion325 decks692 decks
44%synergy
Defile
44%inclusion306 decks692 decks
7%synergy
Go for the Throat
40%inclusion280 decks692 decks
17%synergy
Tainted Strike
38%inclusion263 decks692 decks
35%synergy
Grim Affliction
36%inclusion250 decks692 decks
34%synergy
Deadly Rollick
33%inclusion226 decks692 decks
9%synergy
Infernal Grasp
33%inclusion225 decks692 decks
7%synergy
Withering Torment
29%inclusion117 decks402 decks
-2%synergy
Dismember
29%inclusion200 decks692 decks
18%synergy
Cabal Ritual
27%inclusion188 decks692 decks
9%synergy
Imp's Mischief
27%inclusion184 decks692 decks
3%synergy
Sugar Rush
24%inclusion169 decks692 decks
24%synergy
Supernatural Stamina
22%inclusion153 decks692 decks
15%synergy
Hatred
20%inclusion137 decks692 decks
19%synergy
Astarion's Thirst
19%inclusion133 decks692 decks
18%synergy
Virulent Wound
18%inclusion126 decks692 decks
18%synergy
Sudden Spoiling
18%inclusion126 decks692 decks
9%synergy
Malakir Rebirth
18%inclusion122 decks692 decks
-5%synergy
Consuming Corruption
17%inclusion92 decks530 decks
1%synergy
Snuff Out
17%inclusion118 decks692 decks
4%synergy
Archenemy's Charm
17%inclusion21 decks125 decks
8%synergy
Hero's Downfall
16%inclusion110 decks692 decks
9%synergy
Doom Blade
15%inclusion104 decks692 decks
7%synergy
Fell the Profane
14%inclusion75 decks536 decks
-5%synergy
Force of Despair
13%inclusion92 decks692 decks
6%synergy
Unlikely Aid
13%inclusion89 decks692 decks
12%synergy
Murder
12%inclusion86 decks692 decks
2%synergy
Anoint with Affliction
12%inclusion84 decks692 decks
12%synergy
Baleful Mastery
12%inclusion82 decks692 decks
3%synergy
Withering Boon
10%inclusion70 decks692 decks
6%synergy
Darkness
10%inclusion70 decks692 decks
1%synergy
Sheoldred's Edict
9.4%inclusion65 decks692 decks
-5%synergy
Undying Malice
8.7%inclusion60 decks692 decks
-1%synergy
Culling the Weak
8.2%inclusion57 decks692 decks
-7%synergy
Bitter Triumph
8.2%inclusion57 decks692 decks
-2%synergy
Tragic Slip
7.7%inclusion53 decks692 decks
-13%synergy
Not Dead After All
7.5%inclusion52 decks692 decks
-4%synergy
Rush of Vitality
7.5%inclusion52 decks692 decks
7%synergy
Cut Down
7.4%inclusion51 decks692 decks
3%synergy
Undying Evil
7.4%inclusion51 decks692 decks
4%synergy
Soul Shatter
6.6%inclusion46 decks692 decks
-6%synergy
Unnatural Endurance
6.6%inclusion46 decks692 decks
6%synergy
Slaughter Pact
6.2%inclusion43 decks692 decks
3%synergy
Overkill
5.7%inclusion8 decks141 decks
-2%synergy
Blood Pact
5.5%inclusion38 decks692 decks
1%synergy
Sorceries
Feed the Swarm
54%inclusion376 decks692 decks
3%synergy
Night's Whisper
47%inclusion325 decks692 decks
23%synergy
Crux of Fate
41%inclusion282 decks692 decks
39%synergy
Toxic Deluge
40%inclusion277 decks692 decks
3%synergy
Caress of Phyrexia
38%inclusion263 decks692 decks
37%synergy
Read the Bones
34%inclusion232 decks692 decks
16%synergy
Bubbling Muck
30%inclusion209 decks692 decks
15%synergy
Damnation
27%inclusion187 decks692 decks
6%synergy
Vat Emergence
24%inclusion163 decks692 decks
22%synergy
Reanimate
24%inclusion163 decks692 decks
-15%synergy
Diabolic Tutor
23%inclusion158 decks692 decks
8%synergy
Spread the Sickness
18%inclusion127 decks692 decks
18%synergy
Insatiable Avarice
18%inclusion111 decks616 decks
6%synergy
Mutilate
17%inclusion121 decks692 decks
-1%synergy
Grim Tutor
16%inclusion110 decks692 decks
4%synergy
Blasphemous Edict
13%inclusion44 decks326 decks
-4%synergy
Exsanguinate
13%inclusion87 decks692 decks
-12%synergy
Geth's Summons
12%inclusion86 decks692 decks
12%synergy
Black Sun's Zenith
12%inclusion81 decks692 decks
6%synergy
Feed the Infection
9.0%inclusion62 decks692 decks
8%synergy
Profane Tutor
7.5%inclusion52 decks692 decks
3%synergy
Beseech the Queen
7.4%inclusion51 decks692 decks
1%synergy
In Garruk's Wake
7.2%inclusion50 decks692 decks
3%synergy
Syphon Mind
7.2%inclusion50 decks692 decks
-6%synergy
Torment of Hailfire
6.4%inclusion44 decks692 decks
-9%synergy
Fell
6.3%inclusion30 decks480 decks
3%synergy
Praetor's Grasp
5.3%inclusion37 decks692 decks
1%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion360 decks692 decks
49%synergy
Lightning Greaves
52%inclusion357 decks692 decks
18%synergy
Fireshrieker
46%inclusion318 decks692 decks
44%synergy
Contagion Clasp
42%inclusion291 decks692 decks
39%synergy
Whispersilk Cloak
40%inclusion280 decks692 decks
35%synergy
Contagion Engine
37%inclusion256 decks692 decks
35%synergy
Sword of Truth and Justice
37%inclusion253 decks692 decks
36%synergy
Commander's Plate
36%inclusion247 decks692 decks
30%synergy
Shadowspear
28%inclusion196 decks692 decks
25%synergy
The Darkness Crystal
25%inclusion37 decks147 decks
5%synergy
Leyline Axe
23%inclusion74 decks328 decks
22%synergy
Champion's Helm
21%inclusion142 decks692 decks
19%synergy
Hero's Blade
19%inclusion134 decks692 decks
19%synergy
Trailblazer's Boots
19%inclusion132 decks692 decks
17%synergy
Brotherhood Regalia
17%inclusion87 decks502 decks
15%synergy
Sword of the Animist
17%inclusion116 decks692 decks
13%synergy
Mithril Coat
15%inclusion103 decks692 decks
9%synergy
Cranial Plating
15%inclusion103 decks692 decks
11%synergy
Pact Weapon
15%inclusion102 decks692 decks
13%synergy
Throne of Geth
14%inclusion96 decks692 decks
14%synergy
Sword of Feast and Famine
14%inclusion94 decks692 decks
12%synergy
Genji Glove
14%inclusion19 decks140 decks
12%synergy
Expedition Map
13%inclusion90 decks692 decks
1%synergy
Wayfarer's Bauble
13%inclusion89 decks692 decks
-3%synergy
Doc Ock's Tentacles
12%inclusion12 decks102 decks
12%synergy
Strata Scythe
11%inclusion75 decks692 decks
10%synergy
Grafted Exoskeleton
11%inclusion73 decks692 decks
9%synergy
Inquisitor's Flail
10%inclusion70 decks692 decks
10%synergy
Sword of Vengeance
10%inclusion67 decks692 decks
9%synergy
Hammer of Nazahn
9.0%inclusion62 decks692 decks
8%synergy
Loxodon Warhammer
8.8%inclusion61 decks692 decks
7%synergy
Pip-Boy 3000
8.5%inclusion56 decks660 decks
8%synergy
Bontu's Monument
8.4%inclusion58 decks692 decks
-19%synergy
Prowler's Helm
8.4%inclusion58 decks692 decks
8%synergy
Helm of the Host
8.1%inclusion56 decks692 decks
7%synergy
Darksteel Plate
7.9%inclusion55 decks692 decks
6%synergy
Basilisk Collar
7.7%inclusion53 decks692 decks
5%synergy
Grafted Wargear
7.5%inclusion52 decks692 decks
7%synergy
Sensei's Divining Top
7.5%inclusion52 decks692 decks
-1%synergy
Sword of Wealth and Power
7.4%inclusion49 decks661 decks
7%synergy
Vorpal Sword
7.1%inclusion49 decks692 decks
3%synergy
Buster Sword
6.9%inclusion10 decks144 decks
6%synergy
O-Naginata
6.5%inclusion45 decks692 decks
6%synergy
Whip of Erebos
6.4%inclusion44 decks692 decks
-4%synergy
Sword of Fire and Ice
5.5%inclusion38 decks692 decks
5%synergy
Manifold Key
5.3%inclusion37 decks692 decks
4%synergy
Mask of Avacyn
5.2%inclusion36 decks692 decks
4%synergy
Decimator Web
5.2%inclusion36 decks692 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion347 decks692 decks
48%synergy
Unspeakable Symbol
39%inclusion270 decks692 decks
38%synergy
Kaya's Ghostform
30%inclusion206 decks692 decks
20%synergy
Black Market Connections
22%inclusion152 decks692 decks
-1%synergy
Bad Moon
21%inclusion144 decks692 decks
17%synergy
Fungal Fortitude
18%inclusion127 decks692 decks
17%synergy
Phyresis
15%inclusion107 decks692 decks
13%synergy
No Mercy
15%inclusion105 decks692 decks
8%synergy
Relic Putrescence
15%inclusion103 decks692 decks
15%synergy
Endless Scream
14%inclusion100 decks692 decks
14%synergy
Shade's Form
11%inclusion76 decks692 decks
10%synergy
Dauthi Embrace
11%inclusion74 decks692 decks
9%synergy
Super State
7.9%inclusion10 decks127 decks
8%synergy
Snake Cult Initiation
7.8%inclusion54 decks692 decks
8%synergy
Animate Dead
7.4%inclusion51 decks692 decks
-10%synergy
Black Market
7.1%inclusion49 decks692 decks
-14%synergy
Alien Symbiosis
6.9%inclusion7 decks102 decks
6%synergy
Greed
6.2%inclusion43 decks692 decks
-1%synergy
The Meathook Massacre
5.5%inclusion38 decks692 decks
-12%synergy
Glistening Oil
5.5%inclusion38 decks692 decks
5%synergy
Phyrexian Reclamation
5.2%inclusion36 decks692 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion321 decks692 decks
44%synergy
Liliana of the Dark Realms
28%inclusion193 decks692 decks
14%synergy
Utility Lands
Rogue's Passage
67%inclusion464 decks692 decks
48%synergy
Cabal Coffers
62%inclusion428 decks692 decks
7%synergy
Bojuka Bog
48%inclusion333 decks692 decks
1%synergy
Urborg, Tomb of Yawgmoth
47%inclusion327 decks692 decks
10%synergy
Shizo, Death's Storehouse
45%inclusion309 decks692 decks
34%synergy
Inkmoth Nexus
41%inclusion286 decks692 decks
40%synergy
Cabal Stronghold
38%inclusion260 decks692 decks
2%synergy
Nykthos, Shrine to Nyx
25%inclusion174 decks692 decks
-5%synergy
The Black Gate
21%inclusion144 decks692 decks
17%synergy
Cathedral of War
19%inclusion130 decks692 decks
18%synergy
Castle Locthwain
17%inclusion119 decks692 decks
0%synergy
Command Beacon
17%inclusion116 decks692 decks
9%synergy
War Room
16%inclusion109 decks692 decks
-1%synergy
Reliquary Tower
14%inclusion99 decks692 decks
-17%synergy
Witch's Cottage
13%inclusion88 decks692 decks
-12%synergy
Minas Morgul, Dark Fortress
12%inclusion80 decks692 decks
8%synergy
Urza's Saga
11%inclusion79 decks692 decks
3%synergy
Mortuary Mire
10%inclusion69 decks692 decks
-3%synergy
Temple of the False God
9.4%inclusion65 decks692 decks
1%synergy
Lake of the Dead
9.1%inclusion63 decks692 decks
4%synergy
Strip Mine
8.7%inclusion60 decks692 decks
6%synergy
Takenuma, Abandoned Mire
8.4%inclusion58 decks692 decks
-8%synergy
Barren Moor
7.7%inclusion53 decks692 decks
-3%synergy
Maze of Ith
6.6%inclusion46 decks692 decks
3%synergy
Buried Ruin
6.2%inclusion43 decks692 decks
1%synergy
Phyrexian Tower
5.9%inclusion41 decks692 decks
-18%synergy
Thespian's Stage
5.8%inclusion40 decks692 decks
0%synergy
Spymaster's Vault
5.4%inclusion29 decks536 decks
-4%synergy
Homeward Path
5.1%inclusion35 decks692 decks
3%synergy
Mana Artifacts
Sol Ring
91%inclusion628 decks692 decks
4%synergy
Arcane Signet
65%inclusion452 decks692 decks
3%synergy
Glistening Sphere
46%inclusion320 decks692 decks
45%synergy
Mind Stone
33%inclusion229 decks692 decks
3%synergy
Charcoal Diamond
31%inclusion215 decks692 decks
8%synergy
Staff of Compleation
28%inclusion193 decks692 decks
26%synergy
Heraldic Banner
19%inclusion131 decks692 decks
13%synergy
The Soul Stone
18%inclusion21 decks119 decks
5%synergy
Caged Sun
17%inclusion120 decks692 decks
5%synergy
Thought Vessel
16%inclusion110 decks692 decks
-11%synergy
Fellwar Stone
15%inclusion102 decks692 decks
0%synergy
Lotus Petal
13%inclusion88 decks692 decks
5%synergy
Throne of Eldraine
11%inclusion79 decks692 decks
1%synergy
Commander's Sphere
11%inclusion75 decks692 decks
2%synergy
Mox Opal
10%inclusion70 decks692 decks
7%synergy
Everflowing Chalice
10%inclusion69 decks692 decks
4%synergy
Jeweled Lotus
8.8%inclusion61 decks692 decks
6%synergy
Thran Dynamo
7.5%inclusion52 decks692 decks
1%synergy
Mana Crypt
7.4%inclusion51 decks692 decks
5%synergy
Sceptre of Eternal Glory
6.6%inclusion46 decks692 decks
-2%synergy
Worn Powerstone
6.4%inclusion44 decks692 decks
2%synergy
Gilded Lotus
5.9%inclusion41 decks692 decks
0%synergy
Mox Diamond
5.6%inclusion39 decks692 decks
2%synergy
Nyx Lotus
5.5%inclusion38 decks692 decks
-1%synergy
Phyrexian Atlas
5.1%inclusion35 decks692 decks
5%synergy
Lands
Swamp
95%inclusion657 decks692 decks
0%synergy
Myriad Landscape
24%inclusion165 decks692 decks
-3%synergy
Malakir Rebirth
18%inclusion122 decks692 decks
-5%synergy
Cavern of Souls
16%inclusion111 decks692 decks
9%synergy
Mirrex
15%inclusion107 decks692 decks
15%synergy
Fell the Profane
14%inclusion75 decks536 decks
-5%synergy
Opal Palace
8.2%inclusion57 decks692 decks
7%synergy
Urza's Cave
7.6%inclusion43 decks567 decks
-1%synergy
The Seedcore
7.1%inclusion49 decks692 decks
7%synergy
Snow-Covered Swamp
5.9%inclusion41 decks692 decks
-1%synergy
Command Tower
5.2%inclusion36 decks692 decks
0%synergy
Polluted Delta
5.2%inclusion36 decks692 decks
2%synergy
Bloodstained Mire
5.2%inclusion36 decks692 decks
2%synergy
Verdant Catacombs
5.1%inclusion35 decks692 decks
2%synergy
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