Skithiryx, the Blight Dragon (Commander) - Optimized

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
90decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Bitterbloom Bearer
2.3%inclusion1 decks44 decks
0%synergy
High Synergy Cards
Plague Myr
63%inclusion57 decks90 decks
62%synergy
Plague Stinger
62%inclusion56 decks90 decks
61%synergy
Lashwrithe
60%inclusion54 decks90 decks
56%synergy
Infectious Inquiry
57%inclusion51 decks90 decks
54%synergy
Whispering Specter
53%inclusion48 decks90 decks
53%synergy
Commander's Plate
56%inclusion50 decks90 decks
50%synergy
Shizo, Death's Storehouse
60%inclusion54 decks90 decks
50%synergy
Inkmoth Nexus
50%inclusion45 decks90 decks
49%synergy
Phyrexian Crusader
49%inclusion44 decks90 decks
48%synergy
Hand of the Praetors
46%inclusion41 decks90 decks
45%synergy
Top Cards
Dark Ritual
90%inclusion81 decks90 decks
23%synergy
Jet Medallion
82%inclusion74 decks90 decks
22%synergy
Deadly Rollick
62%inclusion56 decks90 decks
39%synergy
Phyrexian Arena
62%inclusion56 decks90 decks
22%synergy
Crypt Ghast
61%inclusion55 decks90 decks
13%synergy
Toxic Deluge
57%inclusion51 decks90 decks
19%synergy
Cabal Ritual
53%inclusion48 decks90 decks
35%synergy
Feed the Swarm
52%inclusion47 decks90 decks
1%synergy
Black Market Connections
50%inclusion45 decks90 decks
27%synergy
Vraska's Fall
48%inclusion43 decks90 decks
44%synergy
Game Changers
Demonic Tutor
78%inclusion70 decks90 decks
50%synergy
Vampiric Tutor
70%inclusion63 decks90 decks
49%synergy
Ancient Tomb
56%inclusion50 decks90 decks
44%synergy
Necropotence
54%inclusion49 decks90 decks
39%synergy
Mana Vault
49%inclusion44 decks90 decks
42%synergy
Opposition Agent
47%inclusion42 decks90 decks
37%synergy
The One Ring
43%inclusion39 decks90 decks
34%synergy
Chrome Mox
40%inclusion36 decks90 decks
34%synergy
Bolas's Citadel
39%inclusion35 decks90 decks
10%synergy
Orcish Bowmasters
39%inclusion35 decks90 decks
25%synergy
Creatures
Ichor Rats
48%inclusion43 decks90 decks
45%synergy
Dauthi Voidwalker
43%inclusion39 decks90 decks
27%synergy
Sheoldred, the Apocalypse
33%inclusion30 decks90 decks
18%synergy
Phyrexian Obliterator
30%inclusion27 decks90 decks
19%synergy
Gray Merchant of Asphodel
29%inclusion26 decks90 decks
-23%synergy
K'rrik, Son of Yawgmoth
29%inclusion26 decks90 decks
10%synergy
Flesh-Eater Imp
28%inclusion25 decks90 decks
27%synergy
Yawgmoth, Thran Physician
26%inclusion23 decks90 decks
15%synergy
Dark Confidant
23%inclusion21 decks90 decks
16%synergy
Blightbelly Rat
23%inclusion21 decks90 decks
20%synergy
Flensermite
22%inclusion20 decks90 decks
22%synergy
Ichorclaw Myr
18%inclusion16 decks90 decks
17%synergy
Pestilent Syphoner
17%inclusion15 decks90 decks
16%synergy
Reaper of Sheoldred
17%inclusion15 decks90 decks
16%synergy
Myr Convert
17%inclusion15 decks90 decks
16%synergy
Solemn Simulacrum
14%inclusion13 decks90 decks
-9%synergy
Corpse Cur
14%inclusion13 decks90 decks
14%synergy
Magus of the Coffers
13%inclusion12 decks90 decks
6%synergy
Nirkana Revenant
13%inclusion12 decks90 decks
2%synergy
Sheoldred, Whispering One
13%inclusion12 decks90 decks
1%synergy
Core Prowler
12%inclusion11 decks90 decks
12%synergy
Bilious Skulldweller
12%inclusion11 decks90 decks
11%synergy
Septic Rats
12%inclusion11 decks90 decks
10%synergy
Blood Pet
12%inclusion11 decks90 decks
4%synergy
Blightsteel Colossus
12%inclusion11 decks90 decks
12%synergy
Gwenom, Remorseless
9.1%inclusion5 decks55 decks
6%synergy
Massacre Wurm
8.9%inclusion8 decks90 decks
-9%synergy
Agent Venom
8.0%inclusion4 decks50 decks
6%synergy
Leaden Myr
7.8%inclusion7 decks90 decks
1%synergy
Contagious Nim
6.7%inclusion6 decks90 decks
6%synergy
Maha, Its Feathers Night
6.7%inclusion6 decks90 decks
2%synergy
Dread Presence
6.7%inclusion6 decks90 decks
-8%synergy
Silent Arbiter
6.7%inclusion6 decks90 decks
5%synergy
Grafted Butcher
6.7%inclusion6 decks90 decks
6%synergy
Vito, Thorn of the Dusk Rose
6.7%inclusion6 decks90 decks
-4%synergy
Toxic Nim
6.7%inclusion6 decks90 decks
6%synergy
Gulping Scraptrap
6.7%inclusion6 decks90 decks
6%synergy
Phyrexian Vatmother
6.7%inclusion6 decks90 decks
7%synergy
Necroskitter
5.6%inclusion5 decks90 decks
2%synergy
Gix, Yawgmoth Praetor
5.6%inclusion5 decks90 decks
0%synergy
Ornithopter of Paradise
5.6%inclusion5 decks90 decks
3%synergy
Scheming Aspirant
5.6%inclusion5 decks90 decks
5%synergy
Necropede
5.6%inclusion5 decks90 decks
5%synergy
Bloodgift Demon
5.6%inclusion5 decks90 decks
2%synergy
Instants
Imp's Mischief
47%inclusion42 decks90 decks
23%synergy
Dismember
42%inclusion38 decks90 decks
31%synergy
Howl from Beyond
39%inclusion35 decks90 decks
38%synergy
Withering Torment
38%inclusion34 decks89 decks
7%synergy
Infernal Grasp
34%inclusion31 decks90 decks
9%synergy
Malakir Rebirth
32%inclusion29 decks90 decks
10%synergy
Go for the Throat
31%inclusion28 decks90 decks
8%synergy
Snuff Out
29%inclusion26 decks90 decks
16%synergy
Hatred
28%inclusion25 decks90 decks
27%synergy
Tainted Strike
26%inclusion23 decks90 decks
22%synergy
Astarion's Thirst
22%inclusion20 decks90 decks
21%synergy
Sudden Spoiling
22%inclusion20 decks90 decks
13%synergy
Withering Boon
22%inclusion20 decks90 decks
18%synergy
Cut Down
21%inclusion19 decks90 decks
17%synergy
Defile
21%inclusion19 decks90 decks
-16%synergy
Baleful Mastery
21%inclusion19 decks90 decks
12%synergy
Whisper of the Dross
20%inclusion18 decks90 decks
17%synergy
Grim Affliction
18%inclusion16 decks90 decks
16%synergy
Darkness
17%inclusion15 decks90 decks
7%synergy
Fell the Profane
16%inclusion14 decks90 decks
-3%synergy
Culling the Weak
16%inclusion14 decks90 decks
0%synergy
Hero's Downfall
13%inclusion12 decks90 decks
6%synergy
Bitter Triumph
13%inclusion12 decks90 decks
3%synergy
Archenemy's Charm
13%inclusion8 decks60 decks
5%synergy
Force of Despair
12%inclusion11 decks90 decks
4%synergy
Sheoldred's Edict
10%inclusion9 decks90 decks
-4%synergy
Virulent Wound
8.9%inclusion8 decks90 decks
8%synergy
Supernatural Stamina
8.9%inclusion8 decks90 decks
1%synergy
Sugar Rush
7.8%inclusion7 decks90 decks
7%synergy
Slaughter Pact
7.8%inclusion7 decks90 decks
5%synergy
Murder
7.8%inclusion7 decks90 decks
-2%synergy
Tragic Slip
7.8%inclusion7 decks90 decks
-13%synergy
Soul Shatter
6.7%inclusion6 decks90 decks
-6%synergy
Ad Nauseam
6.7%inclusion6 decks90 decks
4%synergy
Unlikely Aid
5.6%inclusion5 decks90 decks
5%synergy
Anoint with Affliction
5.6%inclusion5 decks90 decks
5%synergy
Sorceries
Damnation
46%inclusion41 decks90 decks
25%synergy
Phyresis Outbreak
44%inclusion40 decks90 decks
43%synergy
Bubbling Muck
43%inclusion39 decks90 decks
28%synergy
Crux of Fate
42%inclusion38 decks90 decks
41%synergy
Drown in Ichor
42%inclusion38 decks90 decks
38%synergy
Night's Whisper
40%inclusion36 decks90 decks
16%synergy
Grim Tutor
33%inclusion30 decks90 decks
21%synergy
Sign in Blood
32%inclusion29 decks90 decks
-4%synergy
Imperial Seal
31%inclusion28 decks90 decks
24%synergy
Reanimate
28%inclusion25 decks90 decks
-11%synergy
Caress of Phyrexia
20%inclusion18 decks90 decks
19%synergy
Diabolic Tutor
16%inclusion14 decks90 decks
1%synergy
Read the Bones
16%inclusion14 decks90 decks
-2%synergy
Insatiable Avarice
16%inclusion14 decks90 decks
3%synergy
Mutilate
16%inclusion14 decks90 decks
-3%synergy
Black Sun's Zenith
13%inclusion12 decks90 decks
7%synergy
Profane Tutor
13%inclusion12 decks90 decks
9%synergy
Torment of Hailfire
13%inclusion12 decks90 decks
-2%synergy
Praetor's Grasp
13%inclusion12 decks90 decks
9%synergy
Beseech the Mirror
13%inclusion12 decks90 decks
6%synergy
Blasphemous Edict
13%inclusion11 decks86 decks
-4%synergy
Gix's Command
12%inclusion11 decks90 decks
10%synergy
Beseech the Queen
12%inclusion11 decks90 decks
6%synergy
Vat Emergence
11%inclusion10 decks90 decks
10%synergy
Exsanguinate
11%inclusion10 decks90 decks
-13%synergy
Peer into the Abyss
7.8%inclusion7 decks90 decks
-3%synergy
Spread the Sickness
6.7%inclusion6 decks90 decks
6%synergy
Victimize
6.7%inclusion6 decks90 decks
-19%synergy
Duress
6.7%inclusion6 decks90 decks
0%synergy
Syphon Mind
6.7%inclusion6 decks90 decks
-6%synergy
Thoughtseize
6.7%inclusion6 decks90 decks
2%synergy
Yawgmoth's Will
5.6%inclusion5 decks90 decks
2%synergy
Dark Petition
5.6%inclusion5 decks90 decks
2%synergy
Decree of Pain
5.6%inclusion5 decks90 decks
0%synergy
Rise of the Dark Realms
5.6%inclusion5 decks90 decks
-7%synergy
Utility Artifacts
Lightning Greaves
48%inclusion43 decks90 decks
14%synergy
Nightmare Lash
47%inclusion42 decks90 decks
44%synergy
Swiftfoot Boots
46%inclusion41 decks90 decks
14%synergy
Shadowspear
43%inclusion39 decks90 decks
40%synergy
Blackblade Reforged
39%inclusion35 decks90 decks
36%synergy
Sword of Truth and Justice
32%inclusion29 decks90 decks
31%synergy
Whispersilk Cloak
29%inclusion26 decks90 decks
23%synergy
Contagion Engine
28%inclusion25 decks90 decks
26%synergy
Champion's Helm
26%inclusion23 decks90 decks
24%synergy
The Darkness Crystal
22%inclusion15 decks67 decks
3%synergy
Fireshrieker
22%inclusion20 decks90 decks
20%synergy
Pact Weapon
22%inclusion20 decks90 decks
20%synergy
Leyline Axe
22%inclusion19 decks86 decks
21%synergy
Sensei's Divining Top
21%inclusion19 decks90 decks
13%synergy
Cranial Plating
19%inclusion17 decks90 decks
15%synergy
Contagion Clasp
19%inclusion17 decks90 decks
16%synergy
Expedition Map
19%inclusion17 decks90 decks
6%synergy
Doc Ock's Tentacles
18%inclusion9 decks49 decks
18%synergy
Mithril Coat
18%inclusion16 decks90 decks
12%synergy
Sword of the Animist
18%inclusion16 decks90 decks
14%synergy
Wishclaw Talisman
17%inclusion15 decks90 decks
10%synergy
Sword of Feast and Famine
17%inclusion15 decks90 decks
15%synergy
Hammer of Nazahn
17%inclusion15 decks90 decks
16%synergy
Sword of Wealth and Power
14%inclusion13 decks90 decks
14%synergy
Buster Sword
13%inclusion9 decks67 decks
12%synergy
Brotherhood Regalia
13%inclusion12 decks90 decks
11%synergy
Whip of Erebos
10%inclusion9 decks90 decks
-1%synergy
Thran Power Suit
10%inclusion9 decks90 decks
10%synergy
Strata Scythe
10%inclusion9 decks90 decks
9%synergy
Silver Shroud Costume
10%inclusion9 decks90 decks
9%synergy
Genji Glove
9.2%inclusion6 decks65 decks
8%synergy
Trailblazer's Boots
8.9%inclusion8 decks90 decks
7%synergy
Bontu's Monument
8.9%inclusion8 decks90 decks
-19%synergy
Hero's Blade
8.9%inclusion8 decks90 decks
8%synergy
Loxodon Warhammer
8.9%inclusion8 decks90 decks
8%synergy
O-Naginata
7.8%inclusion7 decks90 decks
8%synergy
Manifold Key
7.8%inclusion7 decks90 decks
6%synergy
Aetherflux Reservoir
7.8%inclusion7 decks90 decks
-2%synergy
Grafted Exoskeleton
7.8%inclusion7 decks90 decks
7%synergy
Wayfarer's Bauble
6.7%inclusion6 decks90 decks
-9%synergy
Strength-Testing Hammer
6.7%inclusion6 decks90 decks
7%synergy
Inquisitor's Flail
6.7%inclusion6 decks90 decks
6%synergy
Vorpal Sword
6.7%inclusion6 decks90 decks
3%synergy
Sword of Vengeance
6.7%inclusion6 decks90 decks
6%synergy
Helm of the Host
5.6%inclusion5 decks90 decks
4%synergy
Sword of Hearth and Home
5.6%inclusion5 decks90 decks
4%synergy
Conqueror's Flail
5.6%inclusion5 decks90 decks
5%synergy
Enchantments
Unspeakable Symbol
46%inclusion41 decks90 decks
45%synergy
Necrogen Communion
27%inclusion24 decks90 decks
25%synergy
Kaya's Ghostform
21%inclusion19 decks90 decks
11%synergy
Phyresis
19%inclusion17 decks90 decks
17%synergy
No Mercy
18%inclusion16 decks90 decks
11%synergy
Contamination
16%inclusion14 decks90 decks
12%synergy
Animate Dead
13%inclusion12 decks90 decks
-4%synergy
The Meathook Massacre
12%inclusion11 decks90 decks
-5%synergy
Super State
11%inclusion7 decks62 decks
11%synergy
Dauthi Embrace
11%inclusion10 decks90 decks
9%synergy
Haunted One
10%inclusion9 decks90 decks
7%synergy
Oubliette
10%inclusion9 decks90 decks
7%synergy
Bitterblossom
10%inclusion9 decks90 decks
-3%synergy
Endless Scream
8.9%inclusion8 decks90 decks
9%synergy
Snake Cult Initiation
8.9%inclusion8 decks90 decks
9%synergy
Bad Moon
8.9%inclusion8 decks90 decks
5%synergy
Alien Symbiosis
8.2%inclusion4 decks49 decks
8%synergy
Black Market
7.8%inclusion7 decks90 decks
-13%synergy
Phyrexian Reclamation
7.8%inclusion7 decks90 decks
-2%synergy
Glistening Oil
7.8%inclusion7 decks90 decks
7%synergy
Exquisite Blood
7.8%inclusion7 decks90 decks
-5%synergy
Leyline of the Void
6.7%inclusion6 decks90 decks
5%synergy
Infernal Darkness
6.7%inclusion6 decks90 decks
6%synergy
Shade's Form
5.6%inclusion5 decks90 decks
5%synergy
Relic Putrescence
5.6%inclusion5 decks90 decks
5%synergy
Planeswalkers
Liliana of the Dark Realms
42%inclusion38 decks90 decks
28%synergy
Vraska, Betrayal's Sting
39%inclusion35 decks90 decks
36%synergy
Tezzeret, Cruel Captain
6.3%inclusion4 decks63 decks
5%synergy
Utility Lands
Cabal Coffers
82%inclusion74 decks90 decks
27%synergy
Urborg, Tomb of Yawgmoth
77%inclusion69 decks90 decks
39%synergy
Rogue's Passage
53%inclusion48 decks90 decks
35%synergy
Karn's Bastion
46%inclusion41 decks90 decks
41%synergy
Urza's Saga
37%inclusion33 decks90 decks
29%synergy
Cabal Stronghold
36%inclusion32 decks90 decks
0%synergy
Bojuka Bog
34%inclusion31 decks90 decks
-12%synergy
Nykthos, Shrine to Nyx
27%inclusion24 decks90 decks
-3%synergy
The Black Gate
23%inclusion21 decks90 decks
20%synergy
Command Beacon
17%inclusion15 decks90 decks
8%synergy
Phyrexian Tower
16%inclusion14 decks90 decks
-9%synergy
Lake of the Dead
16%inclusion14 decks90 decks
10%synergy
Castle Locthwain
16%inclusion14 decks90 decks
-2%synergy
Strip Mine
14%inclusion13 decks90 decks
11%synergy
Takenuma, Abandoned Mire
13%inclusion12 decks90 decks
-3%synergy
Cathedral of War
13%inclusion12 decks90 decks
13%synergy
Reliquary Tower
13%inclusion12 decks90 decks
-18%synergy
Homeward Path
12%inclusion11 decks90 decks
10%synergy
War Room
11%inclusion10 decks90 decks
-5%synergy
Minas Morgul, Dark Fortress
10%inclusion9 decks90 decks
7%synergy
Deserted Temple
7.8%inclusion7 decks90 decks
4%synergy
Temple of the False God
7.8%inclusion7 decks90 decks
0%synergy
Vault of Whispers
6.7%inclusion6 decks90 decks
1%synergy
Emergence Zone
6.7%inclusion6 decks90 decks
3%synergy
Inventors' Fair
6.7%inclusion6 decks90 decks
4%synergy
Wasteland
5.6%inclusion5 decks90 decks
4%synergy
Ghost Quarter
5.6%inclusion5 decks90 decks
3%synergy
Arcane Lighthouse
5.6%inclusion5 decks90 decks
4%synergy
Barren Moor
5.6%inclusion5 decks90 decks
-5%synergy
Buried Ruin
5.6%inclusion5 decks90 decks
0%synergy
Mortuary Mire
5.6%inclusion5 decks90 decks
-8%synergy
Crystal Vein
5.6%inclusion5 decks90 decks
3%synergy
Thespian's Stage
5.6%inclusion5 decks90 decks
0%synergy
Witch's Cottage
5.6%inclusion5 decks90 decks
-19%synergy
Mana Artifacts
Sol Ring
97%inclusion87 decks90 decks
10%synergy
Arcane Signet
69%inclusion62 decks90 decks
6%synergy
Mox Opal
41%inclusion37 decks90 decks
38%synergy
Lotus Petal
40%inclusion36 decks90 decks
33%synergy
The Soul Stone
40%inclusion22 decks55 decks
27%synergy
Mox Diamond
30%inclusion27 decks90 decks
26%synergy
Glistening Sphere
27%inclusion24 decks90 decks
25%synergy
Fellwar Stone
24%inclusion22 decks90 decks
10%synergy
Grim Monolith
23%inclusion21 decks90 decks
20%synergy
Mind Stone
23%inclusion21 decks90 decks
-7%synergy
Staff of Compleation
22%inclusion20 decks90 decks
20%synergy
Throne of Eldraine
19%inclusion17 decks90 decks
8%synergy
Heraldic Banner
18%inclusion16 decks90 decks
12%synergy
Thought Vessel
18%inclusion16 decks90 decks
-9%synergy
Caged Sun
14%inclusion13 decks90 decks
2%synergy
Mox Amber
13%inclusion12 decks90 decks
9%synergy
Charcoal Diamond
11%inclusion10 decks90 decks
-12%synergy
Mox Jasper
11%inclusion9 decks81 decks
11%synergy
Extraplanar Lens
11%inclusion10 decks90 decks
6%synergy
Thran Dynamo
8.9%inclusion8 decks90 decks
3%synergy
Patchwork Banner
7.8%inclusion7 decks90 decks
4%synergy
Gilded Lotus
7.8%inclusion7 decks90 decks
2%synergy
Sceptre of Eternal Glory
7.8%inclusion7 decks90 decks
-1%synergy
Everflowing Chalice
6.7%inclusion6 decks90 decks
1%synergy
Gauntlet of Power
6.7%inclusion6 decks90 decks
3%synergy
Mox Tantalite
5.6%inclusion5 decks90 decks
5%synergy
Lands
Swamp
94%inclusion85 decks90 decks
0%synergy
Cavern of Souls
37%inclusion33 decks90 decks
30%synergy
Malakir Rebirth
32%inclusion29 decks90 decks
10%synergy
Gemstone Caverns
26%inclusion23 decks90 decks
21%synergy
Fell the Profane
16%inclusion14 decks90 decks
-3%synergy
Mirrex
14%inclusion13 decks90 decks
14%synergy
Polluted Delta
13%inclusion12 decks90 decks
10%synergy
Bloodstained Mire
13%inclusion12 decks90 decks
10%synergy
Marsh Flats
13%inclusion12 decks90 decks
10%synergy
Myriad Landscape
12%inclusion11 decks90 decks
-14%synergy
Verdant Catacombs
12%inclusion11 decks90 decks
9%synergy
Urza's Cave
8.9%inclusion8 decks90 decks
0%synergy
Command Tower
7.8%inclusion7 decks90 decks
2%synergy
Snow-Covered Swamp
7.8%inclusion7 decks90 decks
1%synergy
Prismatic Vista
5.6%inclusion5 decks90 decks
3%synergy
Talon Gates of Madara
5.6%inclusion5 decks90 decks
4%synergy
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