Sephiroth, the Savior (Commander) - Expensive Infect

Original Name:

Atraxa, Grand UnifierAtraxa, Grand Unifier

Sephiroth, the Savior
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Enchantments
Battles
Planeswalkers
Utility Lands
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Abundant Countryside
33%inclusion1 decks3 decks
33%synergy
High Synergy Cards
Atraxa, Praetors' Voice
68%inclusion34 decks50 decks
65%synergy
Prologue to Phyresis
84%inclusion42 decks50 decks
60%synergy
Phyresis Outbreak
74%inclusion37 decks50 decks
56%synergy
Venerated Rotpriest
74%inclusion37 decks50 decks
53%synergy
Ixhel, Scion of Atraxa
70%inclusion35 decks50 decks
52%synergy
Infectious Inquiry
72%inclusion36 decks50 decks
49%synergy
Skrelv, Defector Mite
68%inclusion34 decks50 decks
49%synergy
Vraska's Fall
68%inclusion34 decks50 decks
46%synergy
Infectious Bite
60%inclusion30 decks50 decks
42%synergy
Elesh Norn, Mother of Machines
54%inclusion27 decks50 decks
42%synergy
Top Cards
Vraska, Betrayal's Sting
66%inclusion33 decks50 decks
35%synergy
Tekuthal, Inquiry Dominus
66%inclusion33 decks50 decks
28%synergy
Vorinclex, Monstrous Raider
62%inclusion31 decks50 decks
37%synergy
Farseek
54%inclusion27 decks50 decks
15%synergy
Mana Drain
54%inclusion27 decks50 decks
36%synergy
Swords to Plowshares
54%inclusion27 decks50 decks
-5%synergy
Bloated Contaminator
52%inclusion26 decks50 decks
31%synergy
Thrummingbird
52%inclusion26 decks50 decks
21%synergy
White Sun's Twilight
50%inclusion25 decks50 decks
38%synergy
Ezuri, Stalker of Spheres
48%inclusion24 decks50 decks
16%synergy
Game Changers
Rhystic Study
60%inclusion30 decks50 decks
20%synergy
Smothering Tithe
52%inclusion26 decks50 decks
18%synergy
Cyclonic Rift
52%inclusion26 decks50 decks
18%synergy
Demonic Tutor
44%inclusion22 decks50 decks
9%synergy
Vampiric Tutor
42%inclusion21 decks50 decks
13%synergy
Teferi's Protection
36%inclusion18 decks50 decks
18%synergy
The One Ring
34%inclusion17 decks50 decks
13%synergy
Ancient Tomb
28%inclusion14 decks50 decks
7%synergy
Fierce Guardianship
28%inclusion14 decks50 decks
4%synergy
Force of Will
26%inclusion13 decks50 decks
5%synergy
Creatures
Vishgraz, the Doomhive
46%inclusion23 decks50 decks
33%synergy
Contaminant Grafter
46%inclusion23 decks50 decks
30%synergy
Ichor Rats
46%inclusion23 decks50 decks
27%synergy
Birds of Paradise
44%inclusion22 decks50 decks
0%synergy
Skithiryx, the Blight Dragon
44%inclusion22 decks50 decks
29%synergy
Blighted Agent
44%inclusion22 decks50 decks
27%synergy
Elesh Norn, Grand Cenobite
42%inclusion21 decks50 decks
35%synergy
Metastatic Evangel
41%inclusion17 decks41 decks
25%synergy
Evolution Sage
40%inclusion20 decks50 decks
5%synergy
Phyrexian Censor
38%inclusion19 decks50 decks
31%synergy
Sheoldred
38%inclusion19 decks50 decks
32%synergy
Brimaz, Blight of Oreskos
38%inclusion19 decks50 decks
32%synergy
Elesh Norn
36%inclusion18 decks50 decks
30%synergy
Cankerbloom
36%inclusion18 decks50 decks
15%synergy
Jin-Gitaxias, Progress Tyrant
36%inclusion18 decks50 decks
32%synergy
Sheoldred, Whispering One
34%inclusion17 decks50 decks
30%synergy
Jin-Gitaxias
34%inclusion17 decks50 decks
30%synergy
Tyrranax Rex
32%inclusion16 decks50 decks
23%synergy
Sheoldred, the Apocalypse
30%inclusion15 decks50 decks
25%synergy
Necrogen Rotpriest
30%inclusion15 decks50 decks
19%synergy
Norn's Choirmaster
30%inclusion15 decks50 decks
18%synergy
Vorinclex, Voice of Hunger
30%inclusion15 decks50 decks
26%synergy
Bloom Tender
28%inclusion14 decks50 decks
4%synergy
Phyrexian Metamorph
28%inclusion14 decks50 decks
17%synergy
Blightbelly Rat
28%inclusion14 decks50 decks
13%synergy
Delighted Halfling
28%inclusion14 decks50 decks
2%synergy
Plague Myr
26%inclusion13 decks50 decks
18%synergy
Tainted Observer
26%inclusion13 decks50 decks
12%synergy
Phyrexian Swarmlord
26%inclusion13 decks50 decks
14%synergy
Myr Convert
26%inclusion13 decks50 decks
19%synergy
Roaming Throne
24%inclusion12 decks50 decks
21%synergy
Flux Channeler
24%inclusion12 decks50 decks
2%synergy
Glissa, Herald of Predation
24%inclusion12 decks50 decks
19%synergy
Vorinclex
22%inclusion11 decks50 decks
19%synergy
Glissa Sunslayer
22%inclusion11 decks50 decks
18%synergy
Voidwing Hybrid
20%inclusion10 decks50 decks
4%synergy
Y'shtola Rhul
20%inclusion2 decks10 decks
17%synergy
Zopandrel, Hunger Dominus
20%inclusion10 decks50 decks
17%synergy
Esper Sentinel
18%inclusion9 decks50 decks
-12%synergy
Jin-Gitaxias, Core Augur
18%inclusion9 decks50 decks
15%synergy
Dreamtide Whale
17%inclusion7 decks41 decks
-1%synergy
Phyrexian Obliterator
16%inclusion8 decks50 decks
13%synergy
Gix, Yawgmoth Praetor
16%inclusion8 decks50 decks
14%synergy
Noble Hierarch
16%inclusion8 decks50 decks
-11%synergy
Blightsteel Colossus
16%inclusion8 decks50 decks
13%synergy
Bloodroot Apothecary
15%inclusion6 decks40 decks
9%synergy
Wan Shi Tong, Librarian
14%inclusion1 decks7 decks
5%synergy
Badgermole Cub
14%inclusion1 decks7 decks
8%synergy
Displacer Kitten
14%inclusion7 decks50 decks
0%synergy
Plague Nurse
14%inclusion7 decks50 decks
12%synergy
Instants
Experimental Augury
36%inclusion18 decks50 decks
16%synergy
Counterspell
36%inclusion18 decks50 decks
5%synergy
Ephemerate
34%inclusion17 decks50 decks
23%synergy
Heroic Intervention
34%inclusion17 decks50 decks
16%synergy
Tainted Strike
30%inclusion15 decks50 decks
22%synergy
Path to Exile
28%inclusion14 decks50 decks
-4%synergy
Swan Song
22%inclusion11 decks50 decks
-3%synergy
Enlightened Tutor
22%inclusion11 decks50 decks
-3%synergy
Dark Ritual
18%inclusion9 decks50 decks
2%synergy
Worldly Tutor
18%inclusion9 decks50 decks
0%synergy
Arcane Denial
16%inclusion8 decks50 decks
7%synergy
Noxious Revival
14%inclusion7 decks50 decks
6%synergy
Force of Negation
14%inclusion7 decks50 decks
-4%synergy
Radstorm
14%inclusion7 decks50 decks
5%synergy
Dawn's Truce
13%inclusion5 decks40 decks
11%synergy
An Offer You Can't Refuse
12%inclusion6 decks50 decks
-10%synergy
Whisper of the Dross
12%inclusion6 decks50 decks
6%synergy
Assassin's Trophy
12%inclusion6 decks50 decks
-8%synergy
Ghostly Flicker
12%inclusion6 decks50 decks
6%synergy
Anguished Unmaking
12%inclusion6 decks50 decks
0%synergy
Mystical Tutor
12%inclusion6 decks50 decks
-2%synergy
Atomize
10%inclusion5 decks50 decks
-3%synergy
Beast Within
10%inclusion5 decks50 decks
-2%synergy
Momentary Blink
10%inclusion5 decks50 decks
6%synergy
Brokers Confluence
10%inclusion5 decks50 decks
4%synergy
Pact of Negation
10%inclusion5 decks50 decks
-7%synergy
Eerie Interlude
8.0%inclusion4 decks50 decks
3%synergy
Abrupt Decay
8.0%inclusion4 decks50 decks
-6%synergy
Reject Imperfection
8.0%inclusion4 decks50 decks
0%synergy
Cloudshift
8.0%inclusion4 decks50 decks
2%synergy
Strix Serenade
7.3%inclusion3 decks41 decks
4%synergy
Deadly Rollick
6.0%inclusion3 decks50 decks
-7%synergy
Negate
6.0%inclusion3 decks50 decks
-4%synergy
Ripples of Potential
6.0%inclusion3 decks50 decks
-4%synergy
Flawless Maneuver
6.0%inclusion3 decks50 decks
3%synergy
Demonic Consultation
6.0%inclusion3 decks50 decks
-11%synergy
Black Sun's Twilight
6.0%inclusion3 decks50 decks
5%synergy
Aspirant's Ascent
6.0%inclusion3 decks50 decks
5%synergy
Serum Snare
6.0%inclusion3 decks50 decks
1%synergy
Sorceries
Three Visits
44%inclusion22 decks50 decks
23%synergy
Unnatural Restoration
42%inclusion21 decks50 decks
22%synergy
Tezzeret's Gambit
42%inclusion21 decks50 decks
14%synergy
Nature's Lore
40%inclusion20 decks50 decks
14%synergy
Cultivate
34%inclusion17 decks50 decks
2%synergy
Expand the Sphere
30%inclusion15 decks50 decks
22%synergy
Drown in Ichor
30%inclusion15 decks50 decks
14%synergy
Thirsting Roots
24%inclusion12 decks50 decks
12%synergy
Toxic Deluge
22%inclusion11 decks50 decks
7%synergy
Triumph of the Hordes
20%inclusion10 decks50 decks
15%synergy
Kodama's Reach
16%inclusion8 decks50 decks
-2%synergy
Farewell
16%inclusion8 decks50 decks
-1%synergy
Fated Clash
13%inclusion1 decks8 decks
12%synergy
Supreme Verdict
12%inclusion6 decks50 decks
0%synergy
Skyshroud Claim
12%inclusion6 decks50 decks
6%synergy
Rampant Growth
12%inclusion6 decks50 decks
-5%synergy
Reanimate
12%inclusion6 decks50 decks
4%synergy
Breach the Multiverse
12%inclusion6 decks50 decks
10%synergy
Sunfall
12%inclusion6 decks50 decks
7%synergy
Green Sun's Twilight
10%inclusion5 decks50 decks
9%synergy
Culling Ritual
10%inclusion5 decks50 decks
-4%synergy
Imperial Seal
10%inclusion5 decks50 decks
-3%synergy
Contentious Plan
10%inclusion5 decks50 decks
-3%synergy
Geth's Summons
10%inclusion5 decks50 decks
6%synergy
Nature's Rhythm
9.1%inclusion1 decks11 decks
1%synergy
Raise the Palisade
8.0%inclusion4 decks50 decks
8%synergy
Vat Emergence
6.0%inclusion3 decks50 decks
0%synergy
Finale of Devastation
6.0%inclusion3 decks50 decks
-10%synergy
Noxious Assault
6.0%inclusion3 decks50 decks
3%synergy
Utility Artifacts
Realmbreaker, the Invasion Tree
36%inclusion18 decks50 decks
33%synergy
Urza's Incubator
24%inclusion12 decks50 decks
22%synergy
Lightning Greaves
24%inclusion12 decks50 decks
6%synergy
Portal to Phyrexia
20%inclusion10 decks50 decks
18%synergy
The Great Henge
20%inclusion10 decks50 decks
14%synergy
Contagion Engine
12%inclusion6 decks50 decks
-4%synergy
Sword of Truth and Justice
10%inclusion5 decks50 decks
1%synergy
Buster Sword
10%inclusion1 decks10 decks
9%synergy
Insight Engine
10%inclusion1 decks10 decks
5%synergy
The Dominion Bracelet
10%inclusion1 decks10 decks
10%synergy
Ichormoon Gauntlet
10%inclusion5 decks50 decks
-3%synergy
Swiftfoot Boots
10%inclusion5 decks50 decks
-5%synergy
Conjurer's Closet
10%inclusion5 decks50 decks
5%synergy
Grafted Exoskeleton
10%inclusion5 decks50 decks
5%synergy
Dragonfire Blade
9.1%inclusion1 decks11 decks
8%synergy
Panharmonicon
6.0%inclusion3 decks50 decks
-2%synergy
Wishclaw Talisman
6.0%inclusion3 decks50 decks
-5%synergy
Norn's Annex
6.0%inclusion3 decks50 decks
1%synergy
Birthing Pod
6.0%inclusion3 decks50 decks
4%synergy
Enchantments
Norn's Decree
46%inclusion23 decks50 decks
30%synergy
Phyrexian Arena
40%inclusion20 decks50 decks
25%synergy
Skrelv's Hive
36%inclusion18 decks50 decks
26%synergy
Inexorable Tide
34%inclusion17 decks50 decks
6%synergy
Mystic Remora
18%inclusion9 decks50 decks
-9%synergy
Necrogen Communion
18%inclusion9 decks50 decks
11%synergy
Teleportation Circle
16%inclusion8 decks50 decks
9%synergy
Sylvan Library
14%inclusion7 decks50 decks
4%synergy
Phyresis
14%inclusion7 decks50 decks
9%synergy
Food Chain
12%inclusion6 decks50 decks
6%synergy
Brokers Ascendancy
12%inclusion6 decks50 decks
-8%synergy
Doubling Season
10%inclusion5 decks50 decks
-9%synergy
Sphere Grid
10%inclusion1 decks10 decks
7%synergy
Innkeeper's Talent
10%inclusion4 decks40 decks
-2%synergy
Exploration
8.0%inclusion4 decks50 decks
5%synergy
Wild Growth
8.0%inclusion4 decks50 decks
4%synergy
Mirari's Wake
8.0%inclusion4 decks50 decks
3%synergy
Ghostly Prison
8.0%inclusion4 decks50 decks
-2%synergy
Lurking Predators
6.0%inclusion3 decks50 decks
6%synergy
Glistening Oil
6.0%inclusion3 decks50 decks
5%synergy
Phyrexian Reclamation
6.0%inclusion3 decks50 decks
5%synergy
Burgeoning
6.0%inclusion3 decks50 decks
4%synergy
Aura Shards
6.0%inclusion3 decks50 decks
3%synergy
Trouble in Pairs
6.0%inclusion3 decks50 decks
4%synergy
Battles
Invasion of Ikoria
12%inclusion6 decks50 decks
8%synergy
Invasion of Shandalar
6.0%inclusion3 decks50 decks
5%synergy
Planeswalkers
Ajani, Sleeper Agent
38%inclusion19 decks50 decks
24%synergy
The Eternal Wanderer
16%inclusion8 decks50 decks
5%synergy
Nissa, Ascended Animist
8.0%inclusion4 decks50 decks
3%synergy
Teferi, Time Raveler
8.0%inclusion4 decks50 decks
-8%synergy
Tamiyo, Compleated Sage
6.0%inclusion3 decks50 decks
1%synergy
Tamiyo, Field Researcher
6.0%inclusion3 decks50 decks
-9%synergy
Utility Lands
Karn's Bastion
56%inclusion28 decks50 decks
20%synergy
Reliquary Tower
50%inclusion25 decks50 decks
24%synergy
Yavimaya, Cradle of Growth
32%inclusion16 decks50 decks
18%synergy
Boseiju, Who Endures
32%inclusion16 decks50 decks
4%synergy
Urborg, Tomb of Yawgmoth
30%inclusion15 decks50 decks
19%synergy
Inkmoth Nexus
28%inclusion14 decks50 decks
20%synergy
Otawara, Soaring City
14%inclusion7 decks50 decks
-8%synergy
Three Tree City
12%inclusion5 decks41 decks
11%synergy
Cabal Coffers
10%inclusion5 decks50 decks
8%synergy
Evendo, Waking Haven
10%inclusion1 decks10 decks
8%synergy
Mistrise Village
9.1%inclusion1 decks11 decks
0%synergy
Urza's Saga
8.0%inclusion4 decks50 decks
3%synergy
Rogue's Passage
8.0%inclusion4 decks50 decks
-3%synergy
Bojuka Bog
6.0%inclusion3 decks50 decks
-5%synergy
Gaea's Cradle
6.0%inclusion3 decks50 decks
-7%synergy
Mana Artifacts
Sol Ring
96%inclusion48 decks50 decks
9%synergy
Arcane Signet
84%inclusion42 decks50 decks
5%synergy
Glistening Sphere
62%inclusion31 decks50 decks
45%synergy
Chromatic Lantern
46%inclusion23 decks50 decks
10%synergy
Staff of Compleation
30%inclusion15 decks50 decks
19%synergy
Fellwar Stone
30%inclusion15 decks50 decks
-4%synergy
Thought Vessel
24%inclusion12 decks50 decks
14%synergy
Chrome Mox
18%inclusion9 decks50 decks
-1%synergy
Lotus Petal
16%inclusion8 decks50 decks
-3%synergy
Mana Vault
16%inclusion8 decks50 decks
-2%synergy
Jeweled Lotus
14%inclusion7 decks50 decks
12%synergy
Mana Crypt
14%inclusion7 decks50 decks
10%synergy
Mox Opal
14%inclusion7 decks50 decks
6%synergy
Mox Amber
12%inclusion6 decks50 decks
-2%synergy
Mox Diamond
12%inclusion6 decks50 decks
-4%synergy
Talisman of Resilience
10%inclusion5 decks50 decks
5%synergy
Talisman of Dominance
10%inclusion5 decks50 decks
1%synergy
Talisman of Hierarchy
10%inclusion5 decks50 decks
5%synergy
Herd Heirloom
9.1%inclusion1 decks11 decks
8%synergy
Everflowing Chalice
8.0%inclusion4 decks50 decks
-14%synergy
Astral Cornucopia
8.0%inclusion4 decks50 decks
-18%synergy
Decanter of Endless Water
8.0%inclusion4 decks50 decks
4%synergy
Talisman of Curiosity
8.0%inclusion4 decks50 decks
0%synergy
Phyrexian Atlas
8.0%inclusion4 decks50 decks
3%synergy
Talisman of Progress
6.0%inclusion3 decks50 decks
0%synergy
Lands
Command Tower
96%inclusion48 decks50 decks
4%synergy
Forest
84%inclusion42 decks50 decks
6%synergy
Breeding Pool
82%inclusion41 decks50 decks
29%synergy
Swamp
82%inclusion41 decks50 decks
7%synergy
Island
82%inclusion41 decks50 decks
5%synergy
Hallowed Fountain
82%inclusion41 decks50 decks
36%synergy
Plains
78%inclusion39 decks50 decks
2%synergy
Godless Shrine
76%inclusion38 decks50 decks
34%synergy
Windswept Heath
74%inclusion37 decks50 decks
27%synergy
Overgrown Tomb
74%inclusion37 decks50 decks
28%synergy
Flooded Strand
74%inclusion37 decks50 decks
29%synergy
Temple Garden
74%inclusion37 decks50 decks
30%synergy
Misty Rainforest
72%inclusion36 decks50 decks
26%synergy
Watery Grave
72%inclusion36 decks50 decks
23%synergy
Verdant Catacombs
68%inclusion34 decks50 decks
23%synergy
Polluted Delta
68%inclusion34 decks50 decks
23%synergy
Marsh Flats
60%inclusion30 decks50 decks
16%synergy
Exotic Orchard
56%inclusion28 decks50 decks
-9%synergy
Spara's Headquarters
56%inclusion28 decks50 decks
25%synergy
Indatha Triome
56%inclusion28 decks50 decks
25%synergy
Zagoth Triome
52%inclusion26 decks50 decks
21%synergy
Savannah
50%inclusion25 decks50 decks
25%synergy
Tropical Island
48%inclusion24 decks50 decks
23%synergy
Cavern of Souls
48%inclusion24 decks50 decks
37%synergy
Raffine's Tower
46%inclusion23 decks50 decks
18%synergy
Bayou
44%inclusion22 decks50 decks
19%synergy
Tundra
42%inclusion21 decks50 decks
17%synergy
Mana Confluence
42%inclusion21 decks50 decks
12%synergy
Scrubland
40%inclusion20 decks50 decks
16%synergy
Underground Sea
38%inclusion19 decks50 decks
13%synergy
Bountiful Promenade
38%inclusion19 decks50 decks
19%synergy
Undergrowth Stadium
36%inclusion18 decks50 decks
16%synergy
Morphic Pool
34%inclusion17 decks50 decks
16%synergy
Rejuvenating Springs
34%inclusion17 decks50 decks
11%synergy
City of Brass
34%inclusion17 decks50 decks
3%synergy
Sea of Clouds
32%inclusion16 decks50 decks
13%synergy
Reflecting Pool
32%inclusion16 decks50 decks
14%synergy
Vault of Champions
32%inclusion16 decks50 decks
16%synergy
The Seedcore
30%inclusion15 decks50 decks
20%synergy
Path of Ancestry
30%inclusion15 decks50 decks
6%synergy
Bloodstained Mire
26%inclusion13 decks50 decks
9%synergy
Scalding Tarn
24%inclusion12 decks50 decks
5%synergy
Arid Mesa
22%inclusion11 decks50 decks
10%synergy
Wooded Foothills
20%inclusion10 decks50 decks
2%synergy
Starting Town
20%inclusion2 decks10 decks
14%synergy
Sandsteppe Citadel
18%inclusion9 decks50 decks
-6%synergy
Gemstone Caverns
18%inclusion9 decks50 decks
1%synergy
Gemstone Mine
14%inclusion7 decks50 decks
8%synergy
Mirrex
14%inclusion7 decks50 decks
9%synergy
Prismatic Vista
10%inclusion5 decks50 decks
6%synergy
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